J Emerg Med
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Randomized Controlled Trial Comparative Study
Randomized Controlled Noninferiority Trial Comparing Daptomycin to Vancomycin for the Treatment of Complicated Skin and Skin Structure Infections in an Observation Unit.
Incidence of methicillin-resistant Staphylococcus aureus (MRSA) is increasing in complicated skin and skin structure infection (cSSSI) presenting to emergency departments (EDs). Treatment is heterogeneous and can require inpatient admission to an observation unit (OU). Vancomycin is commonly used in the OU for treatment, but increasing MRSA resistance to vancomycin suggests the need for alternatives. Daptomycin is an alternative but it is not known how it compares with vancomycin. ⋯ Daptomycin was not inferior to vancomycin in the treatment of cSSSI in an OU.
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Randomized Controlled Trial
A Randomized Controlled Trial of an Emergency Department Intervention for Patients with Chronic Noncancer Pain.
Emergency Departments (EDs) are beginning to notify their physicians of patients reporting chronic noncancer pain (CNCP) who frequent EDs, and are suggesting that the physicians not prescribe opioids to these patients. ⋯ This intervention constitutes a promising practice that EDs should consider to reduce the number of visits made by frequent visitors with CNCP.