J Emerg Med
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Hypertrophic osteoarthropathy (HOA) is a musculoskeletal pathology that often occurs as a paraneoplastic syndrome. 90% of HOA cases occur secondary to malignancy. 60 to 80% of which are lung cancers. ⋯ We present a case of a 61-year-old man who had worsening knee pain. HOA was incidentally noted on extremity X-ray. The patient was found to have a soft-tissue attenuating mass on chest X-ray. The diagnosis of non-small cell lung cancer was made after bronchoscopy. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: HOA can be an indication of malignancy, most commonly lung cancer, so it is important to recognize the key radiographic findings associated with HOA. When treating patients with bone pain and clubbed digits, emergency physicians should strongly consider screening for more severe primary pathology.
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Caffeine (1,3,7-trimethylxanthine) is a naturally occurring compound found in plants and is the most utilized drug in the world. An estimated 89% of U.S. citizens and 80% of people worldwide consume caffeine on a regular basis. The prevalence of caffeine supplementation by individuals has been increasing in body-weight regulation (e.g., weight loss, body building). When used in excessive amounts it can precipitate serious health consequences, including death. Given this, and the ease of accessibility, caffeine has been seen in intentional overdose. However, suicide attempts via caffeine overdose are rare. In 2017, the American Association of Poison Control Centers reported 3765 cases of caffeine overdose, of which 650 were intentional and none resulted in death from caffeine alone. An ingestion of 5 g (80-100 mg/kg) is likely to prove fatal. ⋯ We present the case of a suicide attempt via caffeine with a reported 20-g overdose, which would be an estimated blood caffeine level of 427.1 mg/L. The patient was given activated charcoal and treated for symptomatic tachycardia and diaphoresis. He was ultimately evaluated by Psychiatry and was discharged home with no adverse outcomes from his intentional overdose. We also examine the physiology of the potential adverse effects of caffeine use and the current literature related to caffeine overdoses. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Caffeine is consumed by billions of individuals globally. It is rarely associated with death, but can cause a variety of adverse effects including tachydysrhythmias, hypokalemia, seizures, and rhabdomyolysis. Caffeine overdoses should be treated immediately with activated charcoal if within the appropriate timeframe of 1-2 h post-ingestion, and special attention should be given to the cardiovascular effects of caffeine, as tachydysrhythmias may prove fatal.
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Households are increasingly stockpiling and producing hand sanitizer amid the coronavirus disease 2019 (COVID-19) pandemic, which can pose an increased risk for unintentional toxicity among children. Despite guidelines for hand sanitizer production published by the World Health Organization, many turn to streaming media for instruction. ⋯ YouTube may not be an accurate source for effective hand sanitizer concoction. Health care providers and parents should be aware of the increased surge in hand sanitizer exposure among children and should take proper precautionary measures.