Ulus Travma Acil Cer
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Ulus Travma Acil Cer · Sep 2017
Separate and synergistic effects of taurolidine and icodextrin in intra-abdominal adhesion prevention.
In our present study, we aimed to evaluate the effects of taurolidine, a blocking agent of fibrin deposition, and icodextrin, a colloid osmotic material that also inhibits fibrin accumulation, and the effect of their application separately and concomittantly in intra-abdominal adhesion prevention. ⋯ Taurolidine and icodextrin, when used alone or together, decrease postoperative intra-abdominal adhesion formation. Macroscopic appearence was not supportive of statistical difference between group 4 and other groups. Microscopic evaluation paves the road for future studies for determining significance when taurolidine and icodextrin are applied concomittantly. Additional experimental studies are required for dose adjustment.
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Ulus Travma Acil Cer · Sep 2017
Evaluation of the systemic antiinflammatory effects of levosimendan in an experimental blunt thoracic trauma model.
Blunt thoracic injury often leads to pulmonary contusion and the development of acute respiratory distress syndrome, which carries a high risk of morbidity and mortality, originating from the local and systemic inflammatory states. This study aimed to investigate the local and systemic antiinflammatory effects of levosimendan in rat models of blunt chest trauma. ⋯ In conclusion, the results showed that in a rat model of PC, the experimental agent levosimendan could reduce neutrophil cell infiltration to damaged pulmonary tissues and the systemic expressions of some cytokines (IL-1ß, IL-6, and NO), thereby partially reducing and/or correcting pulmonary damage. Systemic inflammatory response that occurs after trauma could also be reduced.
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Ulus Travma Acil Cer · Sep 2017
Evaluation of different treatment protocols for combined injury-induced lung injury in rabbits.
This study aims to evaluate the effectiveness of different treatment regimens on combined injury-induced lung injury. ⋯ This study demonstrated the impact of fluid resuscitation on combined injury-induced lung injury. Further, 1:3 fluid resuscitation treatment at the early stage of lung injury after combined lung contusion and burn injury was found to be more effective.
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Ulus Travma Acil Cer · Jul 2017
Comparative StudyComparison of warm fluid and cold fluid resuscitation during uncontrolled hemorrhagic shock model in rats.
This study was designed to compare the effects of resuscitation with cold and warm fluid on survival time, rate and volume of hemorrhage, hemodynamics, hypothermia, coagulopathy, acid-base balance, hematocrit, lactate, and base deficit during uncontrolled hemorrhagic shock (HS) model in rats. ⋯ There is a great need for further experimental and clinical trials on fluid resuscitation in trauma in order to define which fluid should be administered, temperature of the fluid, quantity to be delivered, and duration.
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Ulus Travma Acil Cer · Jul 2017
Eight years of clinical experience with digit replantation: Demographic characteristics and outcomes.
Despite surgical and technical advances in microsurgery, it is still difficult to obtain satisfactory results after replantation of finger amputation. The aim of the present study was to discuss some of the many factors that can affect the success rate of replantation. ⋯ In conclusion, the injury type and personal variables are very important in the rate of replantation success. Knowledge about the effects of different factors on the results of replantation surgery will provide guidance to hand surgeons in order to inform patients and their relatives properly.