Gastroenterology
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Comparative Study
Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer.
We aimed to investigate the clinical utility of circulating tumor cell DNA (ctDNA) and exosome DNA (exoDNA) in pancreatic cancer. ⋯ In a prospective cohort of pancreatic cancer patients, we show how longitudinal monitoring using liquid biopsy samples through exoDNA and ctDNA provides both predictive and prognostic information relevant to therapeutic stratification.