Asian Pac J Allergy
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Asian Pac J Allergy · Mar 2014
An unexpected role for serum uric acid as a biomarker for severity of asthma exacerbation.
Although the increased uric acid (UA) levels in bronchoalveolar lavage fluid and pulmonary tissue homogenate in asthmatic patients or animal models are well established, changes in serum UA(sUA) levels during asthma exacerbation are uncertain. ⋯ sUA levels increased at onset of asthma exacerbation, subsided during the course of exacerbation, and had a negative association with lung function. sUA may be a valuable biomarker for the severity of asthma exacerbation.