Asian Pac J Allergy
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Asian Pac J Allergy · Jun 2017
Randomized Controlled Trial Comparative StudyA comparative pilot study of the efficacy and safety of nebulized magnesium sulfate and intravenous magnesium sulfate in children with severe acute asthma.
Severe asthma attacks are life-threatening, and require serious medical attention. Intravenous MgSO₄ is an efficient medication, proven to improve outcomes. To date, most research has focused on administration of nebulized MgSO₄ in adults with critical asthma. However, its benefits for treating childhood asthma has been little investigated. This study compared the clinical efficacy and adverse effects of nebulized MgSO₄ and intravenous MgSO₄ in the treatment of children with severe acute asthma. ⋯ In this small sample size we demonstrated that nebulized MgSO₄ and intravenous MgSO₄ are both clinically beneficial and safe for Thai children suffering from severe asthma exacerbation.