Clin Cancer Res
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Randomized Controlled Trial Multicenter Study
Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy.
The objective of our study was to determine the clinical relevance of cyclin D1 expression in hormone receptor-positive breast cancer patients who were treated with tamoxifen-based therapy. ⋯ Cyclin D1 expression is an independent poor prognostic factor in women with early-stage, hormone receptor-positive breast cancer who received adjuvant tamoxifen-based therapy.