Aviat Space Envir Md
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Human spaceflight is associated with the loss of body protein. On Earth, insulin is an important factor in the regulation of muscle protein synthesis and breakdown. The objectives of this study were to determine whether insulin resistance occurs in spaceflight, and if the development of insulin resistance is related to the protein loss. ⋯ Dietary intake and urine output were monitored continuously for the four payload crewmembers from 11 d before launch to 7 d after landing for a total of 27 d. Data were obtained on the four payload crewmembers. Results were as follows: 1) the mean inflight C-peptide excretion rates were significantly lower than either the pre- or postflight rates (p < 0.05); and 2) the inflight nitrogen balance decreased as C-peptide excretion increased.
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Aviat Space Envir Md · Dec 1994
Historical ArticlePublishing the Journal of the Aerospace Medical Association: 1929-1981.
The author served as Editor-in-Chief of this Journal from 1959 through 1980, a period which included two title changes and an explosion of information about aerospace medicine and related fields. He reviews the history of the Journal from its establishment in 1929 through the periods of growth during World War II and the coming of the Space Age.