American journal of veterinary research
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To determine the cardiopulmonary effects of anesthesia induced and maintained with isoflurane (ISO) in cats. ⋯ Hypoventilation associated with untoward physiologic responses to 2.0 MAC may be overcome with controlled ventilation, but results in marked reduction in cardiovascular performance; thus, use of 2.0 MAC ISO should be avoided in cats.
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To determine the maximal i.v. administered dose of propofol that would not induce a serious adverse event in nonsedated dogs. ⋯ Respiratory depression and apnea should be expected as potential adverse effects after i.v. administration of propofol to dogs, particularly when administered at rapid rates of infusion.
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To determine reliability of noninvasive methods of arterial oxyhemoglobin saturation (SpO2), end-tidal CO2 concentration (PEtCO2), and blood pressure (BP) determination during periods of hypoxemia and systemic arterial BP perturbations. ⋯ The pulse oximeters tested provided an accurate estimation of SaO2 at SpO2 > 70%. A PEtCO2 value > 55 mm of Hg may represent hypercapnia that is more profound than indicated. Systolic BP determinations were most accurate during hypotensive states and least accurate during hypertension. Diastolic BP measurements were generally more accurate during hypertension than normotension. Accuracy is not appreciably affected by hypotension resulting from vasodilation or blood loss. The tendency to underestimate systemic arterial BP should not interfere with trend detection during unstable clinical conditions.