American journal of veterinary research
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Comparative Study
Evaluation of leukocyte cell surface markers in dogs with septic and nonseptic inflammatory diseases.
To determine whether functional alterations in neutrophils and mononuclear leukocytes are a consistent finding in dogs with inflammatory disease. ⋯ Neutrophils from dogs with septic and nonseptic inflammation circulate in an activated state, and some dogs have decreased MHC class II expression. Many dogs with MODS have a compensatory anti-inflammatory response that may compromise their responses to antimicrobials.
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To determine hemodynamic effects of 3 concentrations of sevoflurane in cats. ⋯ Sevoflurane induces dose-dependent cardiovascular depression in cats that is mainly attributable to myocardial depression.
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Comparative Study
Relationship of bispectral index to minimum alveolar concentration multiples of sevoflurane in cats.
To determine the relationship between bispectral index (BIS) and minimum alveolar concentration (MAC) multiples of sevoflurane in cats. ⋯ Values of BIS are inversely and linearly related to end-tidal sevoflurane concentrations in anesthetized cats, and BIS may be a useful predictor of CNS depression in this species. The consistently low BIS values recorded in this study suggest that clinical BIS end points used to titrate anesthetic agents in humans may not be applicable to cats.