American journal of veterinary research
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To evaluate a bench-top coagulation analyzer for determination of prothrombin time (PT), activated partial thromboplastin time (APTT), and fibrinogen concentration in healthy dogs. ⋯ By use of the mechanical method of analysis, fibrinogen concentrations obtained with a bench-top coagulation analyzer correlated well with results for a conventional laboratory, indicating that the coagulation analyzer is a reliable instrument for determination of this coagulation variable. Coagulation analyzer results for PT and APTT correlated less strongly with those for the conventional laboratory, but they would still be considered clinically reliable.
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Controlled Clinical Trial
Comparison of the effects of caffeine and doxapram on respiratory and cardiovascular function in foals with induced respiratory acidosis.
To determine and compare the effects of caffeine and doxapram on cardiorespiratory variables in foals during isoflurane-induced respiratory acidosis. ⋯ Results indicated that doxapram restored ventilation in a dose-dependent manner in neonatal foals with isoflurane-induced hypercapnia. The effects of caffeine on respiratory function were indistinguishable from those of saline solution.
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To determine agreement for total protein (TP) and albumin concentrations measured by a point-of-care biochemical analyzer in heparinized whole blood and plasma samples obtained from psittacines and compare results with those from a commercial laboratory. ⋯ The analyzer had excellent precision for analysis of heparinized whole blood or plasma samples for TP or albumin concentrations; analyzer values had good agreement with those from a commercial laboratory. The analyzer could be a valid method to measure plasma TP concentrations and provide point-of-care testing in apparently healthy parrots. Biochemical analyzer results for plasma albumin concentration were not validated by results from a commercial laboratory, so conclusions cannot be drawn regarding use of the analyzer in measurement of albumin concentrations in psittacines.
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To compare the cardiopulmonary effects of administration of a solution of xylazine, guaifenesin, and ketamine (XGK) or inhaled isoflurane in mechanically ventilated calves undergoing surgery. ⋯ Administration of XGK resulted in excellent anesthetic induction and maintenance with cardiopulmonary alterations similar to those associated with isoflurane in mechanically ventilated calves.
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Clinical Trial
Use of bispectral index to monitor depth of anesthesia in isoflurane-anesthetized dogs.
To evaluate the correlation between the bispectral index (BIS) and end-tidal isoflurane (ET(ISO)) concentration and compare the use of 3 BIS sensor positions in dogs. ⋯ In dogs, BIS values may not reflect changes in depth of isoflurane anesthesia in the absence of noxious stimulation. Of the 3 sensor positions, frontal-temporal positioning provided better correlation with changes in depth of anesthesia induced via changes in isoflurane concentrations. However, the sensor placements yielded similar results at SQI values > 50.