American journal of veterinary research
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Comparative Study
Assessment of cellular, biochemical, and histologic effects of bipolar radiofrequency treatment of canine articular cartilage.
To assess the cellular, biochemical, and histologic effects of bipolar radiofrequency-generated heat on canine articular cartilage. ⋯ In this study, bipolar radiofrequency treatment had detrimental effects on normal articular cartilage cells and extracellular matrix with probable long-term clinical consequences. The usefulness of radiofrequency for treatment of osteoarthritic articular cartilage requires further investigation.
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Comparative Study
Influence of morphine sulfate on the halothane sparing effect of xylazine hydrochloride in horses.
To quantitate the dose and time-related effects of morphine sulfate on the anesthetic sparing effect of xylazine hydrochloride in halothane-anesthetized horses and determine the associated plasma xylazine and morphine concentration-time profiles. ⋯ Administration of xylazine decreases the anesthetic requirement for halothane in horses. Concurrent morphine administration to anesthetized horses does not alter the anesthetic sparing effect of xylazine or its plasma concentration-time profile.
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Comparative Study
Assessment of the relationship of bispectral index values, hemodynamic changes, and recovery times associated with sevoflurane or propofol anesthesia in pigs.
To evaluate bispectral index (BIS) values in pigs during anesthesia maintained with sevoflurane-fentanyl or propofol-fentanyl as a predictor of changes in hemodynamic parameters and duration of recovery from anesthesia. ⋯ In swine anesthetized with sevoflurane or propofol and undergoing abdominal surgery, the BIS value derived from an electroencephalogram at the end of anesthesia was not useful for predicting the speed of recovery from anesthesia. Moreover, BIS was not useful as a predictor of clinically important changes in arterial blood pressure and heart rate in those anesthetized pigs.
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Comparative Study
Cardiovascular effects of insufflation of the abdomen with carbon dioxide in standing horses sedated with detomidine.
To determine the cardiovascular effects of 60 minutes of abdominal insufflation with CO2 to an intra-abdominal pressure of 15 mm Hg in standing horses receiving a constant rate infusion of detomidine. ⋯ A 60-minute period of abdominal insufflation to an intra-abdominal pressure of 15 mm Hg did not induce significant cardiovascular abnormalities in healthy horses.
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Comparative Study
Evaluation of leukocyte cell surface markers in dogs with septic and nonseptic inflammatory diseases.
To determine whether functional alterations in neutrophils and mononuclear leukocytes are a consistent finding in dogs with inflammatory disease. ⋯ Neutrophils from dogs with septic and nonseptic inflammation circulate in an activated state, and some dogs have decreased MHC class II expression. Many dogs with MODS have a compensatory anti-inflammatory response that may compromise their responses to antimicrobials.