American journal of veterinary research
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Comparative Study
Evaluation of leukocyte cell surface markers in dogs with septic and nonseptic inflammatory diseases.
To determine whether functional alterations in neutrophils and mononuclear leukocytes are a consistent finding in dogs with inflammatory disease. ⋯ Neutrophils from dogs with septic and nonseptic inflammation circulate in an activated state, and some dogs have decreased MHC class II expression. Many dogs with MODS have a compensatory anti-inflammatory response that may compromise their responses to antimicrobials.
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To determine hemodynamic effects of 3 concentrations of sevoflurane in cats. ⋯ Sevoflurane induces dose-dependent cardiovascular depression in cats that is mainly attributable to myocardial depression.
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Comparative Study
Use of the bispectral index as a monitor of anesthetic depth in cats anesthetized with isoflurane.
To determine whether the prestimulation bispectral index (BIS) value or relative change in BIS after noxious stimulation can be used to assess the depth of isoflurane anesthesia in cats. ⋯ The prestimulation BIS value has limited use in assessing anesthetic depth in cats during isoflurane anesthesia. The change in BIS values after a noxious somatic or visceral stimulus was a reliable measure of anesthetic depth and may be a useful measure of early arousal from the hypnotic state.
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To test the hypothesis that isoflurane-anesthetized horses during controlled ventilation and spontaneous ventilation exhibit temporal changes in cerebral hemodynamics, as measured by intracranial pressure and cerebral perfusion pressure, that reflect temporal changes in systemic arterial pressure. ⋯ Cerebral hemodynamics and their association with ventilation mode are altered over time in isoflurane-anesthetized horses and could contribute to decreased cerebral perfusion during prolonged anesthesia.
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To compare the effects of propofol and sevoflurane on the urethral pressure profile in female dogs. ⋯ Sevoflurane is an alternative to propofol for anesthesia in female dogs undergoing urethral pressure profilometry. Use of these anesthetics at appropriate administration rates should reliably distinguish normal from abnormal maximum urethral closure pressures and functional areas. Titration of anesthetic depth is a critical component of urodynamic testing.