American journal of veterinary research
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Comparative Study
Comparison of isoflurane with sevoflurane for anesthesia induction and recovery in adult dogs.
To compare mask anesthesia induction and recovery characteristics between 2 inhalant anesthetic agents: isoflurane and sevoflurane. ⋯ On the basis of these results, sevoflurane is a suitable inhalant anesthetic for mask induction and recovery in adult dogs and appears to have some advantages over isoflurane, including faster and smoother mask induction.
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To determine the effect of bilateral blockade of the pharyngeal branch of the vagus nerve on soft palate function in horses. ⋯ A repeatable, reversible model of DDSP exists that allows further study of the disease. Dysfunction of the neuromuscular group, pharyngeal branch of the vagus nerve and palatinus and palatopharyngeus muscles, may be implicated in the pathogenesis of clinical DDSP.
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To study effects of intermittent positive-pressure ventilation (IPPV) with large tidal volumes and addition of positive end-expiratory pressure (PEEP) on maldistribution of ventilation in anesthetized horses positioned in lateral recumbency. ⋯ Use of PEEP during IPPV changes distribution of inspired gas. Increased in PaO2 can be attributed to improved ventilation-perfusion, especially in the dependent lung, in which previously collapsed lung units might have been reopened and participated again in gas exchange after redistribution of inspired gas. The most pronounced effects of IPPV and PEEP were associated with high airway pressures, which are likely to offset the beneficial effects of the increase of PaO2 on total oxygen availability to the tissues because of the expected negative effects on cardiac output.
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To determine the cardiopulmonary effects of anesthesia induced and maintained with isoflurane (ISO) in cats. ⋯ Hypoventilation associated with untoward physiologic responses to 2.0 MAC may be overcome with controlled ventilation, but results in marked reduction in cardiovascular performance; thus, use of 2.0 MAC ISO should be avoided in cats.
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To determine the maximal i.v. administered dose of propofol that would not induce a serious adverse event in nonsedated dogs. ⋯ Respiratory depression and apnea should be expected as potential adverse effects after i.v. administration of propofol to dogs, particularly when administered at rapid rates of infusion.