Bmc Complem Altern M
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Bmc Complem Altern M · Aug 2014
Neuroprotective effects of melittin on hydrogen peroxide-induced apoptotic cell death in neuroblastoma SH-SY5Y cells.
Free radicals are involved in neuronal cell death in human neurodegenerative diseases. Since ancient times, honeybee venom has been used in a complementary medicine to treat various diseases and neurologic disorders. Melittin, the main component of honeybee venom, has various biologic effects, including anti-bacterial, anti-viral, and anti-inflammatory activities. ⋯ These findings suggest that melittin has potential therapeutic effects as an agent for the prevention of neurodegenerative diseases.