Bmc Pregnancy Childb
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Bmc Pregnancy Childb · Oct 2017
Randomized Controlled TrialA randomized controlled double blind trial comparing the effects of the prophylactic antibiotic, Cefazolin, administered at caesarean delivery at two different timings (before skin incision and after cord clamping) on both the mother and newborn.
Caesarean delivery (CD) increases the risk of postpartum infection by 5 to 20 fold. Prevention of surgical site infection (SSI) is the goal of antibiotic prophylaxis. This study was carried out to assess the optimum timing for prophylactic antibiotic administration and to assess the amount of the antibiotic crossing the placental barrier. ⋯ Pre incision prophylactic antibiotic protected the mother from SSI and febrile illness and decreased the hospital stay significantly.