Hepato Gastroenterol
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Hepato Gastroenterol · Sep 1999
Case ReportsFulminant nonocclusive mesenteric ischemia developing just after esophagectomy.
Nonocclusive mesenteric ischemia (NOMI) is a poorly understood condition, marked by progressive ischemia of the intestine leading to infarction, sepsis and death. The mortality rate remains high. Three cases of NOMI occurred after esophagectomy at our facility. ⋯ Therefore, it should be distinguished from spontaneously developing NOMI. A huge water shift between the intravascular space and the extravascular space during and just after surgery is suspected to have played a major role in the development of post-operative NOMI. Diagnosis and treatment of NOMI after a major surgery are quite difficult.
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Patients with advanced or metastatic cancer have compromised nutritional, metabolic, and immune conditions. Little is known about gastroduodenal perforation in cancer patients. ⋯ Gastroduodenal perforation occurring in cancer patients without chemotherapy had favorable short-term operative results.