J Cardiovasc Surg
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Randomized Controlled Trial
Application of low-volume zero-balanced ultrafiltration and its effect on blood propofol concentration: a randomized controlled trial.
The aim of this study was to evaluate the effectiveness of low-volume zero-balanced ultrafiltration during cardiopulmonary bypass in heart valve replacement surgery. ⋯ Low-volume zero-balanced ultrafiltration performed during cardiopulmonary bypass surgery significantly decreased post-bypass levels of the cytokines, TNF-alpha, IL-6, IL-10, and postoperative cardiac troponin I. Blood propofol concentration was also decreased; however, the depth of anesthesia was not affected significantly.
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Randomized Controlled Trial
L-arginine supplemented nondiluted blood cardioplegia: a clinical trial.
L-arginine was shown to improve protection of the myocardium during coronary artery bypass graft (CABG) surgery. The objective of the present study was to determine the concentration of L-arginine to obtain the most effective protection of the myocardium during CABG surgery. ⋯ Nondiluted blood cardioplegic solution supplemented with 4 mmol/L of L-arginine was associated with a significant decrease of myocardial lactate release after aortic cross-clamping and reperfusion during CABG surgery.