J Neurosurg Sci
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Case Reports
Developmental venous anomaly as a rare cause of obstructive hydrocephalus: literature review and a case report.
Developmental venous anomalies (DVA), previously known as cerebral venous malformations or venous angiomas, are common benign entities often incidentally discovered at MRI examinations. They are non‑pathologic variants of normal deep parenchymal veins that are usually asymptomatic, but they can rarely cause some complications. In this paper we described a rare case of obstructive hydrocephalus caused by a DVA located within the cerebral aqueduct and we also reviewed the previous literature on this topic. ⋯ Despite the fact that DVAs are asymptomatic, they may rarely cause obstructive hydrocephalus because of impairment in the CSF flow. They should be considered in the differential diagnosis of any patient presenting with obstructive hydrocephalus. ETV has been demonstrated as an effective treatment option in the management of obstructive hydrocephalus due to a DVA.
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The objective of this study was to assess the effect of locally administered ibuprofen (IBU) on transected peripheral nerve regeneration and functional recovery. ⋯ Ibuprofen accelerated and improved functional recovery and morphometric indices of sciatic nerve. This study is expected to set a stage for testing the ibuprofen in the human patients.