Ophthal Surg Las Im
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Ophthal Surg Las Im · Mar 2007
Case ReportsCorneal edema and permanent blue discoloration of a silicone intraocular lens by methylene blue.
To report a silicone intraocular lens (IOL) stained blue by inadvertent intraoperative use of methylene blue instead of trypan blue and the results of experimental staining of various lens materials with different concentrations of the same dye. ⋯ This is the first clinicopathological report of IOL discoloration due to intraocular use of methylene blue. This and other tissue dyes may be commonly found among surgical supplies in the operating room and due diligence is necessary to avoid mistaking these dyes for those commonly used during ocular surgery.
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Ophthal Surg Las Im · Mar 2007
Intraocular biodistribution of mono-L-aspartyl chlorin e6 in a primate choroidal neovascularization model.
To describe the biodistribution of a hydrophilic sensitizer, mono-L-aspartyl chlorin e6 (NPe6), in a primate model of choroidal neovascularization (CNV). ⋯ This study demonstrated the selective accumulation of NPe6 photosensitizer and ICG dye within experimental CNV and rapid clearance from the circulation and retinochoroidal tissue.