Minerva anestesiologica
-
Minerva anestesiologica · Nov 1994
Randomized Controlled Trial Clinical Trial[Effects of betamethasone on neuromuscular blockade induced by vecuronium in continuous infusion].
The aim of the study was to determine a possible interaction between a corticosteroid (betamethasone) and vecuronium, a nondepolarizing muscle relaxant. The authors studied 20 patients, ASA I-II, aged 20-54, both sexes, scheduled for abdominal surgery. ⋯ The recovery rate of vecuronium after stopping infusion at 10% recovery was also evaluated. Corticosteroids may interact with non-depolarizing muscle relaxants both in prejunctional and postjunctional acetylcholine receptors by several mechanisms of action.
-
Minerva anestesiologica · Nov 1994
Randomized Controlled Trial Clinical Trial[Early postoperative hypoxemia: incidence and effectiveness of oxygen administration].
To determine the incidence of hypoxaemia and the efficacy of oxygen therapy in the early postoperative period. ⋯ There is a high incidence of clinically unsuspected hypoxaemia in the early postoperative period, the use of supplemental oxygen reduces but does not prevent hypoxaemic episodes, every patient should be monitored continuously with a pulse oximeter in the recovery room.
-
Minerva anestesiologica · Nov 1994
Clinical Trial[Effects of inhalation anesthetics on intracranial pressure and cerebral blood flow velocity].
Inhalation anesthetics diminish cerebrovascular resistance, augmenting cerebral blood flow (CBF) and hematic volume. This may lead to a dangerous increase in intracranial pressure (ICP). It has been observed that isoflurane used in hypocapnia does not appear to cause an increase in ICP equal to that caused by other inhalation anesthetics. ⋯ The results show that during hypocapnia isoflurane causes significant reductions in MAP and CCP whereas ICP and CFV tend to diminish but not significantly. On the contrary, isoflurane in normocapnia causes an increase in ICP and a further and more marked reduction in CPP with a corresponding but not significant increase in CFV. In conclusion, in the light of these results the increase in ICP and the contemporary reduction of MAP would appear to restrict the use of isoflurane in normocapnia in patients with intracranial pathologies.(ABSTRACT TRUNCATED AT 250 WORDS)