Minerva anestesiologica
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Minerva anestesiologica · Jan 2002
Clinical TrialBIS and Ramsay score in critically ill patient: what future?
The recent introduction of BIS has improved the concept of utilizing it as a method for the assessment of the sedation level, thus opening new frontiers in critically ill patients care. Its validity in measuring the hypnotic drug effects has been repeatedly proved, but it has rarely been used in ICU. The aim of this paper is to evaluate the correlation between BIS and Ramsay score and its fluctuations with the sedative dosage variations, as a possible utilization in ICU. ⋯ The data obtained show a good correlation between Ramsay score and BIS.
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Minerva anestesiologica · Jan 2002
[Impact of an integrated treatment approach of the severely injured patients (ISS =/> 16) on hospital mortality and quality of care].
Outcome of severely injured patients is sharply influenced by the level of prehospital and hospital organization. ⋯ The implementation of written protocols for trauma care, the organization of trauma teams, educational programs including ATLS and PTC-IRC Courses and a strategy of early stabilization of limb fractures are associated with a dramatic decrease in hospital mortality for major trauma.
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Minerva anestesiologica · Jan 2002
["Small volume resuscitation" in hypovolemic rats. Effects on microcirculation].
Numerous publications have analysed the hemodynamic effects of "small volume resuscitation" during the initial phases of hemorrhagic shock. Nevertheless nowadays the information about microcirculatory effects are poor. The aim of this study was to estimate the change of tissue perfusion in hypovolemic rats, before and after infusion of Ringer's lactate (RL), hypertonic saline solution (HS) or blood. ⋯ Neither RL nor HS seem as efficient as blood to restore the microcirculatory blood flow in the mesocecum of the rats submitted to hemorrhagic hypovolemia.