Minerva anestesiologica
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Minerva anestesiologica · Mar 2002
Review Comparative StudyNew antidepressants in the treatment of neuropathic pain. A review.
Before 1980s, tricyclics (TCAs) were considered, between antidepressants, the standard in the treatment of different kinds of neuropathic pain, for their action on noradrenergic and serotoninergic pathways, thought the high incidence of side effects. In 1980s a new class of antidepressants has been introduced, the selective serotonin reuptake inhibitors (SSRI). We reviewed some publications, including trials comparing SSRIs with TCAs in pain management. ⋯ The other new antidepressants have been less extensively studied, thus only anecdotal therapeutic results and experimental works have been found and reported. Existing data are surely insufficient to conclude which of these new classes of drugs has the best clinical profile and can be more effective in the treatment of neuropathic pain, but the lower incidence of side effects should be considered. Further evidence-based research in the safety and efficacy of these promising agents in pain relief, is warranted.
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Minerva anestesiologica · Mar 2002
[The use of laryngeal mask airway in esophagogastroduodenoscopy in children].
The use of laryngeal mask airway (LMA) for inducing and maintaining sedation during EGDS has never been reported in the literature but for a brief letter written by Gajraj in 1996. This study proposes the use of sevoflurane administered through LMA. ⋯ The results obtained show that the use of LMA associated to sevoflurane as single inhaling agent can be a valid technique for EGDS in pediatric patients.
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Minerva anestesiologica · Mar 2002
Comparative Study[Epidural analgesia during labor: intermittent bolus or patient controlled administration?].
The aim of the study was to compare efficacy and side effects produced by two techniques of epidural analgesia during labor: intermittent bolus and patient-controlled epidural analgesia. ⋯ This regimen of PCEA proves a viable and safe alternative for epidural analgesia during labor.