Minerva anestesiologica
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Minerva anestesiologica · Mar 2004
Clinical TrialProspective study of the success and efficacy of spinal cord stimulation.
To explore success, the percentage of patients who received definitive implants compared to all patients screened, and efficacy, the percentage of patients that had improved in at least 3 of the 5 parameters after 1 year. In addition, we determined if there was a statistically significant reduction in pain and functional limiting. Finally, we wanted to investigate if the different paresthesia coverage has a different outcome after 1 year of SCS treatment. ⋯ This prospective study confirmed that SCS had good success and efficacy in the treatment of several types of chronic pain. Finally, our study showed the importance of obtaining paresthesia in the affected area but it is not essential to cover the entire painful area.
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Minerva anestesiologica · Mar 2004
Randomized Controlled Trial Comparative Study Clinical TrialPeri-intubation cardiovascular response during low dose remifentanil or sufentanil administration in association with propofol TCI. A double blind comparison.
The aim of this study was to compare the effects on cardiovascular modifications induced by tracheal intubation when low dose infusion of remifentanil or sufentanil are used in association with propofol target controlled infusion. ⋯ In healthy normotensive patients the use of a small dose of either remifentanil or sufentanil after standard midazolam premedication, proved to be an effective strategy to blunt the cardiovascular response to intubation.
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Minerva anestesiologica · Mar 2004
Randomized Controlled Trial Comparative Study Clinical TrialTranexamic acid in primary CABG surgery: high vs low dose.
Prophylactic administration of tranexamic acid decreases bleeding and transfusions after cardiac procedures but it is still unclear what the best dose and the most appropriate timing to get the best results are. ⋯ For elective, first time coronary artery bypass surgery, both dosages of tranexamic acid are equally effective. Theoretically, it seems safer to administer it when patients are protected from thrombus formation by full heparinization.
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Minerva anestesiologica · Mar 2004
Comparative Study Clinical TrialSpinal anaesthesia using hyperbaric 0.75% vs hyperbaric 1% bupivacaine: a double blind comparison.
The aim of this study was to compare the anesthetic effects, potency and postoperative outcome of 0.75% and 1% concentrations of hyperbaric bupivacaine in selective spinal anesthesia. ⋯ No statistically significant differences between the 2 groups for demographic data were found. Group B revealed a faster onset and a more adequate dermatomeric extension (4.1+/-0.8 min vs 6.5+/-1.2 min). Both concentrations guaranteed good hemodynamic stability. Motor offset times were 115.8+/-145 min and 142+/-4.8 min respectively in groups A and B. Sensitive offset times were 197.5+/-12 min and 168+/-5.2 min respectively in groups A and B. No statistically relevant differences were noticed for intraoperative Bromage, sensitive block or for postoperative motor and sensitive offset time, diuresis time and deambulation time. There are no advantages of 1% hyperbaric bupivacaine over 0.75% for selective spinal anesthesia, while several disadvantages presented shorter duration of postoperative analgesia and higher incidence of headache.