Surg Neurol
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The purpose of the present study was to investigate the relationship between serum concentrations of the immunoglobulin-like superfamily, selectins, hsCRP, and the development of DIND in patients with aneurysmal SAH. ⋯ Serum levels of ICAM-1, VCAM-1 and hsCRP during the early and late period following SAH correlate with DIND.
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Instead of surgical intervention, endovascular treatment with GDC has become an important tool to treat intracranial aneurysm in recent years. However, intraoperative aneurysm rupture remains a devastating complication for physicians. Rapid and precise packing with coils and external ventricular drainage are advised. Stereotactic aspiration of an enlarged intracerebral hematoma caused by intraprocedural perforation of aneurysm has been rarely discussed as a method of dealing with this consequence. ⋯ The role of stereotactic aspiration in the management of an enlarged hematoma due to intraprocedural perforation of aneurysm during coil embolization may have further implications, and it may be considered as an alternative treatment to open clot evacuation for intracranial hemorrhages with aneurysms.
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The objective of the study was to improve the accuracy of computer-assisted pedicle screw installation in the spine. This study evaluates the accuracy of computer-assisted pedicle screw placement with separate spinal reference clamp placement and registration on each instrumented vertebra for thoracolumbar spine fractures. ⋯ Separate registration increases accuracy of screw placement in thoracolumbar pedicle instrumentation. Separate spinal reference clamp placement in the instrumented vertebra provides real-time virtual imaging that decreases the possibility of downward displacement during manual installation of the screw.
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Chondroitin sulfate proteoglycans are up-regulated in the spinal cord after SCI, creating a molecular barrier inhibitory to axon growth. Chondroitinase ABC degrades CSPGs in vitro and in vivo. ⋯ Intrathecal ChABC administration caused a slight decrease in CSPGs in the scar after a laceration SCI with a minimal increase in sensory axonal regeneration into and across the laceration gap.