World Neurosurg
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Review Meta Analysis
Incidence of Subsidence of 7 intervertebral Devices in Anterior Cervical Discectomy and Fusion: A Network Meta-analysis.
Subsidence is an incapacitating complication in anterior cervical discectomy and fusion (ACDF). However, the debate over which of the intervertebral devices is associated with lower incidence of subsidence remains to be settled. ⋯ CP and IP resulted in a lower rate of subsidence than cage alone or ICAG. Zero-P and ROI-C cages led to similar subsidence rates with plate. All types of intervertebral device can be applied to both single-level and multilevel ACDF with comparable subsidence rate.
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Quantitative gait analysis has been established as a valuable tool for functional assessment and evaluation of intervention efficacy in lumbar spinal stenosis (LSS). We aimed to bolster the limited evidence on the specific aspects of gait that are altered in LSS. ⋯ This study demonstrated significant alterations in clinically measurable gait parameters in patients with LSS compared with healthy subjects. Future studies should assess the value of these gait parameters for objective clinical assessment of functional status and intervention efficacy through correlation with currently used subjective tools and comparison at preoperative and postoperative time points. Specific gait alterations identified in patients with LSS may be valuable for clinical objective assessment of functional status and intervention efficacy.
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Factors associated with visual outcomes after transcranial surgery for large-to-giant pituitary adenomas have not been fully elucidated. ⋯ Visual compromise is still an unignorable complication during transcranial surgery for large-to-giant pituitary adenomas. Subarachnoid space invasion indicated by preoperative magnetic resonance imaging was an independent negative predictor for visual outcomes after surgery.
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Obsessive-compulsive disorder (OCD) is a chronic disease with a lifetime prevalence of 3% and is associated with severe impairment in familial and socio-occupational functioning. Gamma ventral capsulotomy (GVC) is a treatment choice in carefully chosen patients, with few published reports. In this study, we aimed to report the efficacy and safety of GVC in 21 patients with treatment-resistant OCD. ⋯ Gamma ventral capsulotomy is a reasonable treatment method in select patients with treatment-resistant OCD.
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Malignant peripheral nerve sheath tumors (MPNSTs) occur sporadically, in patients with neurofibromatosis 1, and in patients with prior radiation therapy. The incidence of unrelated prior malignancies and family history of malignancy in patients with MPNSTs has not been previously described. ⋯ Patients with sporadic MPNSTs had a high incidence of personal and family history of malignancy. The genetics associated with sporadic MPNSTs include RAS and p53 mutations, which are found in multiple oncologic processes and tumor-forming syndromes. This suggests an underlying genetic predisposition to formation of malignancies, including MPNSTs.