World Neurosurg
-
Gastric stromal tumor is a potentially malignant mesenchymal tumor that is difficult to diagnose before surgery. Computed tomography is the most commonly used tool for diagnosing gastrointestinal stromal tumor. This study combined peripheral nerve analysis and computed tomography for diagnosis and prognosis of gastrointestinal stromal tumor. This study shows that computed tomography can accurately show the location, shape, and size of gastric scrotal tumors and has important clinical value in identifying benign and malignant tumors as well as early clinical judgment and treatment and prognosis.
-
The pathogenesis and clinical characteristics of sciatica caused by pregnancy were summarized to reduce the incidence of misdiagnoses and missed diagnoses. The sciatic nerve, tibial nerve, common peroneal nerve, sural nerve, superficial peroneal nerve, saphenous nerve, and lateral femoral cutaneous nerve were examined using ultrasonography for 7 imaging features, including the shape and internal structure of the peripheral nerves of the lower extremities. ⋯ We found no significant differences in the peripheral nerve cross-sectional area between the left and right legs but did find a positive correlation with body mass index and age.
-
To investigate factors associated with poor clinical outcomes in patients with acute ischemic stroke undergoing endovascular therapy. ⋯ Diabetes, tandem occlusion, high NIHSS score at admission, and general anesthesia were independent risk factors associated with a poor 90-day outcome and should be considered a reference by neurointerventionalists in guiding their clinical decision-making.
-
Deep brain stimulation (DBS) is under investigation as a treatment for therapy-refractory obsessive-compulsive disorder (OCD). As a crucial part of the anxiety circuit, the bed nucleus of stria terminalis (BNST) has been proposed as a target for DBS in OCD. Here, we investigate clinical outcomes and safety of DBS in the BNST in a series of 11 participants with severe therapy-refractory OCD. ⋯ BNST DBS is a promising therapy in severe therapy-refractory OCD. Our results are in line with previous publications regarding effect and safety profile. Nevertheless, DBS for OCD remains an investigational therapy and should therefore be performed in multidisciplinary clinical studies.
-
Case Reports
Sporadic malignant perineurioma - a rare diagnosis among malignant peripheral nerve sheath tumors.
Malignant perineurioma is a rare subset of malignant peripheral nerve sheath tumors (MPNSTs) with ultrastructural and immunohistochemical features of perineurial differentiation, distinguishing it from other MPNSTs, which typically demonstrate Schwannian features. The clinical course and prognosis of this rare tumor is not well defined. ⋯ Patients in our series presented at varied stages of disease. Clinical courses after diagnosis of malignant perineurioma, where follow-up was available, were largely uncomplicated with regard to recurrence and metastatic disease. Careful follow-up is indicated, and further work is needed to characterize the clinical course of these rare tumors.