World Neurosurg
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Patients with acute ischemic stroke (AIS) have limited evidence regarding the relationship between blood urea nitrogen and albumin (BUN/ALB). Aiming to investigate the relationship between the BUN/ALB ratio and poor outcomes in AIS patients at 3-months was the purpose of this study. ⋯ The BUN/ALB ratio and poor outcomes in AIS patients show a nonlinear correlation. For AIS patients, a BUN/ALB ratio of approximately 0.326 is associated with the lowest risk of adverse outcomes at 3 months. Specifically, for non-smoking AIS patients, a BUN/ALB ratio of approximately 0.295 is associated with the lowest risk of adverse outcomes at 3 months.
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Glioblastoma is the most aggressive primary brain tumor, and the outlook for patients is usually pessimistic. Numerous ongoing studies have focused on enhancing the survival rate of glioblastoma patients. This study aims to analyze the research trends surrounding glioblastoma survival and facilitate studying recent topics to provide insight into the perspective, research fields, and international collaborations. ⋯ The most active countries in this field are the United States, followed by China, Germany, and Italy, respectively. Considering the significance of monitoring the studies in glioblastoma patients, the current research has shown promising results in stratifying patient survival as a valuable tool for prognosis and prediction and eventually guiding treatment decisions. Using the results of this study, glioblastoma researchers can identify their potential colleagues and research gaps in this field.
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Cerebrospinal Fluid (CSF) diversion via shunt placement is a common neurosurgical intervention. Keen's Point is a widely used landmark for accessing the trigone of the lateral ventricle; however, it lacks clinical validation. This study re-evaluates Keen's Point scalp parameters using magnetic resonance imaging (MRI) to identify an ideal shunt entry point based on 3D reconstructions. ⋯ This modified Keen's Point is a reliable landmark for ventriculostomy. Incorporating PCA into preoperative planning enhances catheter placement accuracy, providing a prominent approach to shunting at Keen's Point.
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This study aims to evaluate the prognostic factors and survival outcomes of pediatric patients with pineal region tumors using a large population-based registry. ⋯ Early age at diagnosis and aggressive histological types such as pineoblastomas are associated with poorer outcomes. Future research should focus on refining therapeutic protocols that integrate the histological and molecular profiles of these tumors.
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Cavernous malformations are low-flow fragile vascular lesion, prone to extralesional bleeding that can occur in the cerebral hemispheres, the brainstem, or the spinal cord. We report the case of a 32-years-old right-handed male patient with acute-onset headaches associated with right-sided tinnitus, right-sided hemianesthesia, and binocular diplopia related to cranial nerve IV palsy. Neuroimaging displayed left-sided isolated cavernous malformation of the inferior tectal plate, with evidence of extralesional bleeding. ⋯ At the 3 months follow-up consultation, symptoms had improved aside from diplopia which required wearing prism eyeglasses. Tectal cavernous malformations account for 18% of midbrain cavernomas. It was explained that surgical excision using the supracerebellar infratentorial approach would be performed within 2 months following a second extralesional bleeding episode causing disabling symptoms.