World Neurosurg
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Endovascular transmural targeting of cervical and cranial perivascular structures is a novel approach for minimally invasive delivery of therapeutics. Components of the autonomic nervous system are in close anatomic proximity to major cervical vasculature and, therefore, represent potential targets for intervention. The superior cervical ganglion (SCG) is a discrete structure of interest for this approach, as sympathetic blockade may have therapeutic effects for various conditions. Variability of SCG location and its relationship to large cervical vessels, and the feasibility of endovascular transmural targeting has not been elucidated. ⋯ This is the first anatomical study to provide pertinent targeting information for endovascular transmural access to the SCG using CTA. In most cases, endovascular transmural access to the SCG is anatomically feasible from the proximal cervical ICA.
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Due to the substantial lack of data from Iraq on ventriculoperitoneal shunt (VPS) complications, this study aims to examine the various types of complications after VPS surgery in Baghdad Medical City. ⋯ Our study showed the significant complication rate associated with VPS surgeries for hydrocephalus, particularly VPS infections and obstruction. There were no significant age-related differences in VPS complication rates across age groups.
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Myelomeningocele (MMC) disproportionately affects low-resource areas and regions without mandatory folic acid fortification. No specific literature exists on the distribution of research output regarding neurosurgical management of myelomeningocele worldwide in relation to regional disease burden. We aimed to examine the country of origin and patient population of published papers on myelomeningocele and topics related to neurosurgical management of MMC, to determine whether these were proportionate to disease burden. ⋯ The global literature concerning neurosurgical management of myelomeningocele originates predominantly from HICs. Published experiences of myelomeningocele patients from LICs/LMICs are scarce, even though they comprise the majority of the affected population. Neurosurgeons and other health professionals must address this mismatch between disease burden and publication volume in order to inform practice, policy, and advocacy for myelomeningocele care worldwide.
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To explore the relevant variables that contribute to deep vein thrombosis (DVT) among spinal cord injury patients undergoing inpatient rehabilitation and to build and validate a nomogram model that predicts DVT risk. ⋯ Prothrombin time, D-dimer level, age and Caprini score are independent related factors for DVT among spinal cord injury patients undergoing inpatient rehabilitation. According to the variables mentioned previously, a nomogram model was constructed that can accurately and easily predict DVT risk among spinal cord injury patients undergoing inpatient rehabilitation. This facilitates the early identification of high-risk groups and the timely implementation of prevention, treatment, rehabilitation, and nursing strategies by clinical medical staff.