World Neurosurg
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Case Reports
Imaging feature of Leukoencephalopathy with calcifications and cysts (Labrune syndrome).
Labrune syndrome is an uncommon central nervous system disorder characterized by leukoencephalopathy, cerebral calcifications, and cysts on brain imaging. The basic pathology is microangiopathy resulting from a mutation in the SNORD118 gene. Radiological imaging is the hallmark of the disease.