World Neurosurg
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Previous work in anaplastic astrocytoma (AA) demonstrated that the survival benefit from gross total resection (GTR) is modified by age and tumor location. Here, we determined the influence of age and tumor location on survival benefit from GTR in diffuse astrocytoma (DA). ⋯ Age and tumor location modify the survival benefit derived from GTR in DA. Survival patterns in SEER imperfectly correlated with mIDH prevalence in TCGA, suggesting that tumor grade and mIDH status convey nonredundant prognostic information in select clinical contexts.
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Case Reports
Hemorrhagic Atypical Planum Sphenoidale Meningioma with Intermittent Vision Loss-A Rare Presentation of Apoplexy.
Symptoms that mimic pituitary apoplexy may be encountered with other neoplastic or infectious lesions. ⋯ As the most common benign intracranial tumors, meningiomas should remain in the differential for patients presenting with apoplectiform symptoms.
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Delayed cerebral infarction after aneurysmal subarachnoid hemorrhage (aSAH) still remains the leading cause of disability in patients that survive the initial ictus. It has been shown that computed tomography perfusion (CTP) imaging can detect hypoperfused brain areas. The aim of this study was to evaluate if a single acute CTP examination at time of neurologic deterioration is sufficient or if an additional baseline CTP increases diagnostic accuracy. ⋯ Acute CTP examination in case of suspected vasospasm-induced neurologic deterioration after aSAH has the highest diagnostic accuracy to detect misery perfusion. Additional baseline CTP is not needed. The most sensitive parameter to detect critically perfused brain areas is TTD.
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Comparative Study
Endocrine and metabolic outcomes following transcranial and endoscopic endonasal approach for primary resection of craniopharyngiomas.
Craniopharyngiomas have traditionally been resected through the transcranial approaches (TCA). The endoscopic endonasal approach (EEA) has recently been developed as an alternative for surgeons, but controversy remains regarding which approach has better outcomes. We compared the endocrine and metabolic outcomes of TCA and EEA in patients who underwent primary resection of craniopharyngiomas. ⋯ EEA may provide the same gross total resection rate for craniopharyngioma as TCA while providing better protection of anterior pituitary function.