World Neurosurg
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This study aimed to clarify the relationship between histone deacetylase 3 (HDAC3) expression and the prognosis as well as the grade of patients with glioma. ⋯ HDAC3 mRNA was expressed more in glioma than in the normal glial cell line. Low HDAC3 mRNA expression levels predicted better OS. HDAC3 expression could be a biomarker to discriminate glioma grade.
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Titanium mesh implants (TMIs) are used for various purposes in craniotomy. Although delayed implant exposure and thinning of the overlying skin are well-known complications, the mechanism has not yet been elucidated. We reviewed our cases and propose a mechanism for TMI exposure. ⋯ We believe that the key factor resulting in delayed titanium mesh exposure is the pressure gradient between the atmosphere and the intracranial space. Fluctuation of this gradient exerts dynamic stress on the tissue in the mesh holes and the adjacent tissue, resulting in tissue damage and implant exposure.
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Effect of Sagittal Spinal Balance on the Outcome of Decompression Surgery for Lumbar Canal Stenosis.
Although sagittal spinal balance is known to affect the outcome of spinal deformity surgery, its effect on simple decompression surgery is not well understood. ⋯ Sagittal spinal balance significantly affected the outcome of patients undergoing decompression surgery for lumbar canal stenosis, the knowledge of which may serve better patient management.