World Neurosurg
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Negative pressure wound therapy (NPWT) has been used for postsurgical wound management across various disciplines, including spinal surgery. However, its efficacy in reducing wound infection rates after posterior thoracolumbar spine surgery remains uncertain. ⋯ NPWT significantly reduced infection rates in patients with multiple comorbidities, suggesting its potential benefit in managing wound infections in this subgroup. This finding is particularly relevant for an urban, minority patient population, highlighting the importance of tailored wound care strategies.
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This study aims to develop a fully automated, computed tomography (CT)-based deep learning (DL) model to segment ossified lesions of the posterior longitudinal ligament and to measure the thickness of the ossified material and calculate the cervical spinal cord compression factor. ⋯ The proposed DL model effectively detects and separates ossification foci in OPLL on CT images. It exhibits comparable performance to radiologists in quantifying spinal cord compression metrics.
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Malignant glioma progresses rapidly and shows poor prognosis, but clinically applicable blood plasma-based biochemical tumor markers remain lacking. This study aimed to develop a diagnostic system using probe electrospray ionization mass spectrometry (PESI-MS) and a machine-learning logistic regression model to detect plasma changes at various time points in a murine glioma model. ⋯ These results indicate that PESI-MS combined with machine learning-based diagnostics in blood plasma could be a promising approach to accurate detection of malignant glioma.
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To compare the efficacy and safety of unilateral biportal endoscopic lumbar interbody fusion (UBE-LIF) and endoscopic lumbar interbody fusion (Endo-LIF) in the treatment of lumbar degenerative diseases in lumbar degenerative diseases. ⋯ Postoperative pain and safety were comparable between the two endoscopic procedures.The UBE-LIF procedure was shorter, whereas the Endo-LIF had less total blood loss and a shorter recovery time.