J Orofac Pain
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Randomized Controlled Trial Comparative Study Clinical Trial
The efficacy of appliance therapy in patients with temporomandibular disorders of mainly myogenous origin. A randomized, controlled, short-term trial.
To compare the short-term efficacy of treatment with a stabilization appliance compared with that of a non-occlusal, control appliance in patients with temporomandibular disorders (TMD) of mainly myogenous origin. ⋯ The results of this short-term evaluation suggest that the stabilization appliance is more effective in alleviating symptoms and signs in patients with TMD of mainly myogenous origin than a control, non-occlusal appliance. The stabilization appliance can therefore be recommended for the therapy of these patients.
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To determine the temporomandibular joint (TMJ) pressure pain threshold (PPT) in female patients with rheumatoid arthritis (RA) and TMJ involvement in comparison with healthy females, in order to determine its clinical usefulness for local pain assessment. ⋯ This study shows that the PPT of the TMJ in RA patients is lower than in healthy individuals and that it can be used for pain assessment. However, the clinical use of the TMJ PPT and PPT ratio measurements alone is limited from a diagnostic point of view.
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Randomized Controlled Trial Clinical Trial
Analgesic efficacy of low-dose diclofenac versus paracetamol and placebo in postoperative dental pain.
To compare the efficacy and safety of diclofenac-K (12.5 mg) vs paracetamol (500 mg) and placebo given in a flexible dosage regimen to treat pain resulting from extraction of impacted third molar teeth. ⋯ An initial double-dose of diclofenac-K (2 x 12.5 mg) or paracetamol (2 x 500 mg) adequately relieved the most intense postoperative pain, and the flexible multiple dose regimen (1 or 2 tablets) maintained adequate pain relief thereafter. Most patients needed only 1-tablet doses following the initial 2-tablet dose.
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Clinical Trial Controlled Clinical Trial
A human model of intraoral pain and heat hyperalgesia.
To examine, in a double-blind and placebo-controlled crossover manner, the effect of topical application of capsaicin on the alveolar mucosa with a battery of intraoral quantitative sensory testings (QST) in 16 healthy volunteers. ⋯ The intraoral capsaicin pain model is associated with signs of heat hyperalgesia, but not mechanical hyperalgesia. Since the somatosensory sensitivity is not well characterized in most orofacial pain conditions, mainly due to lack of tradition and techniques, intraoral QST may provide a better description of the somatosensory sensitivity and underlying mechanisms in orofacial pain conditions.
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Randomized Controlled Trial Clinical Trial
Counseling and physical therapy as treatment for myofascial pain of the masticatory system.
To prospectively evaluate the effectiveness of a treatment regimen comprising counseling and physical therapy in patients with myofascial pain of the masticatory system, and to explore whether the duration of the physical therapy offered (4 vs 6 weeks) would influence the treatment result. ⋯ A conservative approach involving counseling and physical therapy resulted in significant improvement in parameters of pain and jaw function in patients with myofascial pain. A controlled study will be necessary to elucidate the specific effectiveness of physical therapy over counseling or no treatment.