J Orofac Pain
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Clinical Trial Controlled Clinical Trial
A human model of intraoral pain and heat hyperalgesia.
To examine, in a double-blind and placebo-controlled crossover manner, the effect of topical application of capsaicin on the alveolar mucosa with a battery of intraoral quantitative sensory testings (QST) in 16 healthy volunteers. ⋯ The intraoral capsaicin pain model is associated with signs of heat hyperalgesia, but not mechanical hyperalgesia. Since the somatosensory sensitivity is not well characterized in most orofacial pain conditions, mainly due to lack of tradition and techniques, intraoral QST may provide a better description of the somatosensory sensitivity and underlying mechanisms in orofacial pain conditions.
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Randomized Controlled Trial Clinical Trial
Spread and referral of experimental pain in different jaw muscles.
To test the hypothesis that there would be no differences in perceived pain intensity and spread and referral of pain evoked by injection of a similar amount of hypertonic saline into 6 different jaw-muscle sites in healthy female subjects. ⋯ The data suggest no major differences in pain sensitivity between the examined jaw-muscle sites, but pain in the anterior temporalis muscle spreads to a larger area independent of pain intensity. There are subtle but detectable differences in the location and referral of pain patterns between jaw muscles. This will be helpful in the differential diagnosis of myofascial temporomandibular disorder pain.
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Randomized Controlled Trial Clinical Trial
Analgesic efficacy of low-dose diclofenac versus paracetamol and placebo in postoperative dental pain.
To compare the efficacy and safety of diclofenac-K (12.5 mg) vs paracetamol (500 mg) and placebo given in a flexible dosage regimen to treat pain resulting from extraction of impacted third molar teeth. ⋯ An initial double-dose of diclofenac-K (2 x 12.5 mg) or paracetamol (2 x 500 mg) adequately relieved the most intense postoperative pain, and the flexible multiple dose regimen (1 or 2 tablets) maintained adequate pain relief thereafter. Most patients needed only 1-tablet doses following the initial 2-tablet dose.
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To investigate the course of myofascial pain defined by Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) over a period of 5 years, and to identify prognostic factors from baseline data. ⋯ Muscle disorders classified by RDC/TMD are predominantly chronic or fluctuating pain conditions, with a modest probability (31%) of remission.
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To apply the Finnish version of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) Axis I to assess the occurrence of symptoms, signs, and specific subgroups of TMD, and to study the associations between the most common diagnoses and categoric demographic characteristics (gender, age group, marital status, type of work). ⋯ The RDC/TMD appear to be of benefit in diagnosing TMD among these multiprofessional media personnel and thus may be suggested for use among nonpatient populations.