J Orofac Pain
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Randomized Controlled Trial
Effects of low-dose intramuscular ketorolac on experimental pain in the masseter muscle of healthy women.
To investigate the effect of a low dose of intramuscular (im) ketorolac compared with lidocaine (LA) in a double-blinded, randomized, and controlled trial. ⋯ A low dose of im ketorolac has a significant and immediate analgesic effect on HS-evoked jaw muscle pain but significantly less than LA. A local anesthetic-like effect may be the underlying mechanism.
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Comparative Study
Mandibular function is severely impaired in systemic sclerosis patients.
To evaluate the presence of temporomandibular disorders (TMD) in systemic sclerosis (SSc) patients and its possible association with the severity of skin involvement. ⋯ Severe signs of TMD according to the anamnestic and clinical Helkimo indices were very frequent in SSc patients.
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To estimate the clinically important change (CIC) on a 100-mm visual analog scale for pain intensity (VAS-PI) by relating it to the patient's global impression of change (PGIC) in patients with chronic temporomandibular disorder (TMD) pain and to assess the dependency of the CIC on their baseline pain scores. ⋯ Providing a standard definition of the CIC adds to the interpretability of study results, ie, the estimates will aid in understanding individual patient outcomes.
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To evaluate the antinociceptive effects of citronellal (CTL) on formalin-, capsaicin-, and glutamate-induced orofacial nociception in mice and to investigate whether such effects might involve a change in neural excitability. ⋯ These results suggest that CTL might represent an important tool for management and/or treatment of orofacial pain.
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To derive reliable and valid revised Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) Axis I diagnostic algorithms for clinical TMD diagnoses. ⋯ Revised RDC/TMD Axis I TMD diagnostic algorithms are recommended for myofascial pain and joint pain as reliable and valid. However, revised clinical criteria alone, without recourse to imaging, are inadequate for valid diagnosis of two of the three disc displacements as well as osteoarthritis and osteoarthrosis.