J Orofac Pain
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Comparative Study
Changes in human primary motor cortex activity during acute cutaneous and muscle orofacial pain.
To use functional magnetic resonance imaging (fMRI) to determine whether orofacial cutaneous or muscle pain is associated with changes in primary motor cortex (M1) activity that outlast the duration of perceived pain, and whether these M1 changes are different during cutaneous pain compared with muscle pain. ⋯ The transient contralateral M1 signal intensity increase during orofacial muscle pain may underlie escape-like motor patterns. However, once the initial threat has subsided, longer-term reductions in M1 activity and/or excitability may occur to aid in minimizing movement of the affected part, an effect consistent with the general proposals of the Pain Adaptation Model.
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To investigate the effects of morphine on mechanical allodynia following compression of the trigeminal ganglion in the rat. ⋯ These results suggest that the application of a high dose of morphine may be of great benefit in treating trigeminal neuralgia-like nociception.
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Comparative Study
Migraine is the most prevalent primary headache in individuals with temporomandibular disorders.
To assess the prevalence of primary headaches (HA) in adults with temporomandibular disorders (TMD) who were assessed in a specialty orofacial pain clinic, as well as in controls without TMD. ⋯ TMD was associated with increased primary HA prevalence rates. Migraine was the most common primary HA diagnosis in individuals with TMD.
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Comparative Study
Painful conditioning stimuli of the craniofacial region evokes diffuse noxious inhibitory controls in men and women.
To compare the modulatory effects of tonic mechanical or thermal craniofacial painful conditioning stimuli on pain sensitivity in craniofacial and spinal test sites in healthy men and women. ⋯ This study has documented that mechanical and thermal painful tonic stimuli applied to the craniofacial region can evoke diffuse noxious inhibitory control (DNIC)-like effects in the craniofacial region as well as spinally innervated areas, but without sex differences.
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Comparative Study
Mandibular function is severely impaired in systemic sclerosis patients.
To evaluate the presence of temporomandibular disorders (TMD) in systemic sclerosis (SSc) patients and its possible association with the severity of skin involvement. ⋯ Severe signs of TMD according to the anamnestic and clinical Helkimo indices were very frequent in SSc patients.