Cardiovasc Diabetol
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Cardiovasc Diabetol · Jan 2016
Multicenter Study Observational StudyLower-extremity amputation as a marker for renal and cardiovascular events and mortality in patients with long standing type 1 diabetes.
We evaluated the risks of renal and cardiovascular complications, and mortality associated with lower extremity amputation (LEA) in patients with type 1 diabetes. ⋯ Patients with LEA have a higher risk of ESRD, myocardial infarction and cardiovascular and non-cardiovascular mortality. Our results highlight the importance of LEA as a key-predictor for major vascular events and premature death in type 1 diabetic patients.