Kardiol Pol
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Controlled Clinical Trial
Verification of the left ventricular ejection fraction from gated myocardial perfusion studies (GSPECT).
The perfusion study (which may be obtained using SPECT or GSPECT technology within six hours of administration of the radionuclide Tc-99m-MIBI) reflects the regional blood supply to the left ventricular [LV] myocardium at the time of radionuclide administration (i.e. at rest, at peak exercise, or at peak vasodilatation), while the values of EF, EDV, and ESV measured using GSPECT are parameters of LV contractility at the time of image acquisition (i.e. at rest or in a nearresting state following exercise or vasodilatation). Planar radionuclide ventriculography [RNV] is, however, considered to be the most accurate method for calculating LVEF. ⋯ In order to complement data on myocardial perfusion, the GSPECT-QGS technique should be optimally used to calculate LV contractility parameters at rest (as opposed to post-exercise or post-dipyridamole), and include a range of normal values for EF, EDV, and ESV, obtained using QGS. Of note, EF measurements by GSPECT are more accurate for dilated than non-dilated ventricles.
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A case of a 51-year old man, suffering from drug-resistant hypertension, complaining of hypersomnia and fatigue during the day, is presented. In the course of diagnostic procedures the diagnosis of sleep apnea syndrome was established. Continuous positive airway pressure (CPAP) therapy was successfully started. Examination carried out 3 months later revealed good response to pharmacological treatment with normal levels of blood pressure.