Journal of the neurological sciences
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Randomized Controlled Trial Multicenter Study
Nerve safety of tanezumab, a nerve growth factor inhibitor for pain treatment.
To evaluate peripheral nerve safety and clinical efficacy of tanezumab in patients with painful osteoarthritis. ⋯ Tanezumab has a modulating effect on pain, does not appear to increase neurological safety signals, and offers a potentially promising, novel approach in treatment of pain.