The Journal of pediatrics
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The Journal of pediatrics · Sep 2002
Relation of sleep state to hypoxemic episodes in ventilated extremely-low-birth-weight infants.
To determine whether hypoxemic episodes in ventilated extremely-low-birth-weight infants correlate with specific behavioral states. ⋯ Higher proportions of hypoxemia were found during indeterminate sleep and arousal compared with active sleep and quiet sleep. We speculate that motor activity during sleep disruption could prevent effective mechanical delivery of ventilator breaths and contribute to episodes of hypoxemia. Our results suggest that strategies promoting uninterrupted sleep cycling analogous to the intrauterine state could improve ventilatory stability.