The Journal of pediatrics
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The Journal of pediatrics · Jul 2011
Review Meta AnalysisTonsillectomy in children with periodic fever with aphthous stomatitis, pharyngitis, and adenitis syndrome.
To seek evidence supporting a role for tonsillectomy or adenotonsillectomy in the management of affected children with periodic fever with aphthous stomatitis, pharnygitis, and adenitis (PFAPA) syndrome. ⋯ Surgery appears to be a possible option for management of PFAPA syndrome. Available evidence is limited, however, and the precise role of surgery remains to be clarified. We suggest considering this option when symptoms markedly interfere with the child's quality of life and medical treatment has failed.