The Journal of pediatrics
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The Journal of pediatrics · Jun 2006
Renal replacement therapy in the treatment of confirmed or suspected inborn errors of metabolism.
Analysis of mortality and risk factors for mortality in the use of renal replacement therapy to correct metabolic disturbances associated with confirmed or suspected inborn errors of metabolism. ⋯ Renal replacement therapy can correct the metabolic disturbances that accompany suspected or confirmed inborn errors of metabolism. Our experience demonstrates an approximately 60% mortality rate associated with renal replacement treatment, with more than 70% of survivors living longer than 2 years.
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The Journal of pediatrics · Jun 2006
Indomethacin prophylaxis, patent ductus arteriosus, and the risk of bronchopulmonary dysplasia: further analyses from the Trial of Indomethacin Prophylaxis in Preterms (TIPP).
To determine the risk of bronchopulmonary dysplasia (BPD) in subgroups of infants with and without patent ductus arteriosus (PDA) who were randomized to indomethacin prophylaxis or placebo, and to examine whether adverse drug effects on edema formation and oxygenation may explain why indomethacin prophylaxis does not reduce BPD. ⋯ Harmful side effects on oxygenation and edema formation may explain why indomethacin prophylaxis does not prevent BPD even though it reduces PDA.
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The Journal of pediatrics · Jun 2006
Randomized Controlled Trial Comparative StudyNeonatal laryngoscope intubation and the digital method: a randomized controlled trial.
We compared digital intubation (DI) and laryngoscope intubation (LI) in newborns. The success rate was 90.5% for DI and 50% for LI (P = .004). It took 8.2 seconds to complete the DI and 13.1 seconds to complete the LI (P = .007). DI should be considered to be an option for neonatal intubation.