The Journal of pediatrics
-
The Journal of pediatrics · Aug 2003
Acute chylothorax in children: selective retention of memory T cells and natural killer cells.
To assess for immunodeficiency in patients with hypogammaglobulinemia in the setting of draining acute chylothorax. ⋯ Draining chylothorax resulted in IgG and lymphocyte depletion with preferential retention of memory T cells and natural killer cells in the circulation. Overall, protective-specific antibody levels and T cell function were maintained. IVIG administration did not lead to discernible protection from infectious complications in this small group of patients.
-
The Journal of pediatrics · Jul 2003
Randomized Controlled Trial Clinical TrialEffect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial.
To evaluate the efficacy and safety of ganciclovir therapy in neonates with congenital cytomegalovirus (CMV) disease. ⋯ Ganciclovir therapy begun in the neonatal period in symptomatically infected infants with CMV infection involving the central nervous system prevents hearing deterioration at 6 months and may prevent hearing deterioration at > or =1 year. Almost two thirds of treated infants have significant neutropenia during therapy.
-
The Journal of pediatrics · May 2003
Comparative StudyDoes age play a role in recovery from sports-related concussion? A comparison of high school and collegiate athletes.
To evaluate symptoms and neurocognitive recovery patterns after sports-related concussion in high school and college athletes. ⋯ Caution and systematic evaluation should be undertaken before returning athletes with concussion to competition. Sole reliance on the self-report of the athlete may be inadequate. Preliminary data may suggest a more protracted recovery from concussion in high school athletes.