The Journal of pediatrics
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The Journal of pediatrics · Sep 2002
Relation of sleep state to hypoxemic episodes in ventilated extremely-low-birth-weight infants.
To determine whether hypoxemic episodes in ventilated extremely-low-birth-weight infants correlate with specific behavioral states. ⋯ Higher proportions of hypoxemia were found during indeterminate sleep and arousal compared with active sleep and quiet sleep. We speculate that motor activity during sleep disruption could prevent effective mechanical delivery of ventilator breaths and contribute to episodes of hypoxemia. Our results suggest that strategies promoting uninterrupted sleep cycling analogous to the intrauterine state could improve ventilatory stability.
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The Journal of pediatrics · Aug 2002
Case ReportsMethemoglobinemia in an infant receiving nitric oxide after the use of eutectic mixture of local anesthetic.
High levels of methemoglobinemia can cause tissue hypoxia and cyanosis. We report the case of a 7-month-old girl with pulmonary dysplasia receiving inhaled nitric oxide who had cyanosis caused by methemoglobinemia after prolonged use of a eutectic mixture of local anesthetics cream.
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The Journal of pediatrics · Jul 2002
Randomized Controlled Trial Clinical TrialEfficacy of albuterol inhalation in treatment of hyperkalemia in premature neonates.
To evaluate the efficacy of inhaled albuterol for treatment of hyperkalemia in premature neonates by conducting a prospective, randomized placebo-controlled and double-blinded clinical trial. ⋯ Albuterol inhalation may be useful in rapidly lowering serum potassium levels in premature neonates.
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The Journal of pediatrics · Jul 2002
Randomized Controlled Trial Clinical TrialPhysical therapy and cognitive-behavioral treatment for complex regional pain syndromes.
Complex regional pain syndromes (CRPS; type 1, reflex sympathetic dystrophy, and type 2, causalgia) involve persistent pain, allodynia, and vasomotor signs. We conducted a prospective, randomized, single-blind trial of physical therapy (PT) and cognitive-behavioral treatment for children and adolescents with CRPS. Children 8 to 17 years of age (n = 28) were randomly assigned to either group A (PT once per week for 6 weeks) or group B (PT 3 times per week for 6 weeks). ⋯ Recurrent episodes were reported in 50% of patients, and 10 patients eventually received sympathetic blockade. Most children with CRPS showed reduced pain and improved function with a noninvasive rehabilitative treatment approach. Long-term functional outcomes were also very good.