The Journal of pediatrics
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The Journal of pediatrics · Aug 2013
Clinical TrialAchieving targeted pulse oximetry values in preterm infants in the delivery room.
To determine whether resuscitation teams can better maintain newborn transitional oxygen saturation (SpO₂) values within a prespecified target range using a graphical display of the targets and real-time SpO₂ data compared with using only numerical oximeter values. ⋯ SpO₂ values were maintained within a specified target range for significantly longer in preterm neonates resuscitated using the TOTS display compared with those resuscitated without TOTS.
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The Journal of pediatrics · Jul 2013
Randomized Controlled Trial Multicenter StudyThe NOFLO trial: low-flow nasal prongs therapy in weaning nasal continuous positive airway pressure in preterm infants.
To determine if low-flow nasal prongs therapy with room air, compared with no treatment, facilitates weaning from nasal continuous positive airway pressure (NCPAP) in very low birth weight (VLBW, birth weight <1500 g) infants. ⋯ In this study, we did not demonstrate a benefit of low-flow room air via nasal prongs to wean VLBW infants from NCPAP.
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The Journal of pediatrics · Jul 2013
Multicenter StudyVariation in resource utilization across a national sample of pediatric emergency departments.
To describe variations in emergency department (ED) quality measures and determine the association between ED costs and outcomes for 3 pediatric conditions: asthma, gastroenteritis, and simple febrile seizure. ⋯ We observed variation in quality measures for patients presenting to pediatric EDs with common conditions. Higher costs were not associated with lower hospitalization or ED revisit rates.
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The Journal of pediatrics · Jul 2013
Randomized Controlled TrialQuantitative end-tidal carbon dioxide monitoring in the delivery room: a randomized controlled trial.
To investigate the utility of continuous quantitative end-tidal CO2 (Etco2) monitoring for managing assisted ventilation in the delivery room (DR). ⋯ Etco2 monitoring in the DR did not reduce the proportion of admission Pco2 levels outside of the prespecified range in a population of infants supported mostly with noninvasive ventilation.
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The Journal of pediatrics · Jul 2013
Distribution of early structural lung changes due to cystic fibrosis detected with chest computed tomography.
To examine the distribution of early structural lung changes in clinically stable infants and young children with cystic fibrosis using chest computed tomography (CT). ⋯ Early structural lung disease is heterogeneously distributed in the lung. Quantitative scoring tools for studies using chest CT as an end point, and mechanistic studies that seek to better understand the pathogenesis of early cystic fibrosis lung disease, should take account of this differential topographic expression of disease early in life.