Life sciences
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The discovery of different shades of fat has been implicated in the pathogenesis of obesity-related metabolic disorders. However, the effects of early and intermittent exposure to cold temperature on systemic metabolic changes in adult life remain unclear. ⋯ Intermittent exposure to cold temperature in early life may improve systemic glucose homeostasis and induce WAT "browning", suggesting that an ambient cold temperature exposure may serve as a promising intervention to metabolic disorders.