Life sciences
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Peripheral nerve injury represents a substantial clinical problem with insufficient or unsatisfactory treatment options. Current researches have extensively focused on the new approaches for the treatment of peripheral nerve injuries. Carnosine is a naturally occurring pleotropic dipeptide and has many biological functions such as antioxidant property. In the present study, we examined the regenerative ability of carnosine after sciatic nerve crush injury using behavioral, biochemical, histological and ultrastructural evaluations. ⋯ Carnosine treatment might be considered as a therapeutic agent for peripheral nerve regeneration and its functional recovery.
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This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief and the authors, as panels from Figure 6F appear as similar to panels from Figure 2B of the article published by Ming-Quan Gao, Hui Gao, Mei Han, Kai-Li Liu, Jian-Jun Peng and Yan-Tao Han in the American Journal of Cancer Research 7 (2017) 1501–1514 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523031/ and Figures 2E and 3E of the article published by Meizhi Wang, Hui Gao, Haijun Qu, Jing Li, Kaili Liu and Zhiwu Han in Pharmacological Reports 70 (2018) 963–971 https://doi.org/10.1016/j.pharep.2018.04.006. Also, the Vehicle panel from Figure 7E appears as similar to the Vehicle panel from Figure 3D of the article published by Bo Liu and Shuo Yu in Biomedicine & Pharmacotherapy 107 (2018) 243–253 https://doi.org/10.1016/j.biopha.2018.07.177. Figure 7E appears also as similar to Figure 6(b) of the article published by Mei Han, Hui Gao, Jing Xie, Yin-ping Yuan, Quan Yuan, Ming-quan Gao, Kai-li Liu, Xue-hong Chen, Yan-tao Han and Zhi-wu Han in Acta Pharmacologica Sinica volume 40 (2019) 666–676 https://doi.org/10.1038/s41401-018-0159-7. Moreover, panels from Figure 7F appear as similar to panels from Figure 7E of the Reference [1], Figure 6D of the Reference [2], Figure 6C of the Reference [3], Figure 8C of the Reference [4], Figure 8D of the Reference [5] and Figure 6B of the Reference [6]. One of the conditions of submission of a paper for publication is that authors declare explicitly that their work is original and has not appeared in a publication elsewhere. Re-use of any data should be appropriately cited. As such this article represents a severe abuse of the scientific publishing system. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected during the submission process.