European journal of obstetrics, gynecology, and reproductive biology
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Eur. J. Obstet. Gynecol. Reprod. Biol. · Mar 2016
Randomized Controlled Trial Comparative StudyCarbetocin compared to oxytocin in emergency cesarean section: a randomized trial.
To evaluate the uterotonic effect of carbetocin compared with oxytocin in emergency cesarean delivery. ⋯ Fewer women in the carbetocin arm needed additional uterotonics but perioperative blood loss, severe postpartum hemorrhage, blood transfusion and operating time were not different.
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Eur. J. Obstet. Gynecol. Reprod. Biol. · Feb 2016
Prenatal exposure to zidovudine and risk for ventricular septal defects and congenital heart defects: data from the Antiretroviral Pregnancy Registry.
To assess the risk for ventricular septal defects and congenital heart defects following zidovudine exposure during pregnancy using data from the Antiretroviral Pregnancy Registry. ⋯ ClinicalTrials.gov identifier: NCT01137981.
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Eur. J. Obstet. Gynecol. Reprod. Biol. · Feb 2016
Randomized Controlled Trial Multicenter StudyLow-molecular-weight heparin and aspirin in the prevention of recurrent early-onset pre-eclampsia in women with antiphospholipid antibodies: the FRUIT-RCT.
To examine whether combined treatment with low-molecular-weight heparin (LMWH) and aspirin reduces recurrent hypertensive disorders of pregnancy (HD: pre-eclampsia, eclampsia or HELLP syndrome) in women with antiphospholipid antibodies (aPLA) and a previous delivery for HD and/or small-for-gestational-age (SGA) birthweight before 34 weeks gestation. ⋯ In this population of women with aPLA, who had previously had an early delivery for HD and/or SGA prior to 34 weeks gestation, combined LMWH and aspirin treatment started before 12 weeks gestation in a subsequent pregnancy did not show reduction of onset of recurrent HD either <34 weeks gestation or irrespective of gestational age, compared with aspirin alone.
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Eur. J. Obstet. Gynecol. Reprod. Biol. · Feb 2016
Pessary placement in the prevention of preterm birth in multiple pregnancies: a propensity score analysis.
In asymptomatic women with a multiple pregnancy and short cervix prophylactic use of a cervical pessary might reduce preterm birth. We assessed the possible treatment effects of pessary use in pregnancy duration and for poor perinatal outcome. ⋯ In this cohort study with propensity score analysis, pessary use did not prevent preterm birth in asymptomatic women with a multiple pregnancy and short cervix.
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Eur. J. Obstet. Gynecol. Reprod. Biol. · Feb 2016
The impact of sperm morphology on the outcome of intrauterine insemination cycles with gonadotropins in unexplained and male subfertility.
To determine the impact of sperm morphology on success of intrauterine insemination (IUI) in unexplained and male subfertility. ⋯ Morphological evaluation is not a reliable parameter alone for predicting pregnancy outcome in unexplained infertility. In male subfertility, post-wash normal sperm morphology percentage higher than 4.5 increases the probability of live birth.