The American journal of clinical nutrition
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Randomized Controlled Trial Clinical Trial
Effect of a lifestyle intervention on bone mineral density in premenopausal women: a randomized trial.
The positive association between body weight and bone mineral density (BMD) is well documented; in contrast, the effect of changes in body weight on BMD is not well understood, particularly, in normal-weight populations. ⋯ The intervention group, who modified their lifestyle to lose weight, had a higher rate of BMD loss at the hip and lumbar spine than did the weight-stable control group. Recommendations for weight loss must be made with consideration that such an endorsement may result in BMD loss.