The American journal of clinical nutrition
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Results of experimental studies suggest that deviations in gut microbiota composition predispose to excessive energy storage and obesity. The mother influences the original inoculum and the development of infant microbiota, which in turn is associated with later weight gain. ⋯ Gut microbiota composition and weight are linked, and mother's weight gain is affected by microbiota. Microbiota modification before and during pregnancy may offer new directions for preventive and therapeutic applications in reducing the risk of overweight and obesity.
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Individual energy requirements of overweight and obese adults can often not be measured by indirect calorimetry. ⋯ For US adults aged 18-65 y with a body mass index of 25 to 40, the REE can best be estimated with the Mifflin equation. For overweight and obese Dutch adults, there appears to be no accurate equation.